When to Make Patients NPO

Maggie Doyle


This section covers non-medical reasons for patients to be made NPO in the hospital, including for surgeries, procedures, and imaging studies. See sections on individual medical conditions (e.g., SBO) for NPO considerations. 

As a rule of thumb, anything that requires general anesthesia requires the patient to be NPO for 8 hours. By convention, patients are made NPO at midnight.

Circumstance

Order

Special Considerations

Surgeries, exams under anesthesia (EUA), requiring general anesthesia

OR

Endoscopic evaluations (EGD, ERCP)
NPO at Midnight Includes bronchoscopies and other procedures with the interventional pulmonology team
Interventional Radiology procedures NPO at Midnight* Some procedures (superficial biopsies, certain line placements) are done under local anesthesia. Can err on the side of caution and make NPO unless specifically noted or communicated by IR.
Cardiac catheterization NPO at midnight* Certain guidelines say 6 hours for solids, 2 hours for clear liquids. Many interventionalists are okay with this (and there’s good data to back it up – see below). However, the rule of thumb is to place NPO at MN order.
Cardiac stress Imaging (Stress CMR, nuclear stress tests) NPO 6 hours before + No caffeine for 24 hours before test If a patient is scheduled for an afternoon stress imaging study, can let them have breakfast and make NPO 6 hours before. If not yet scheduled, safest to make NPO at midnight. Order “No caffeine for 24 hours” as a nursing communication, make sure to emphasize with patient and the nurse
Cardiac PET NPO 4-6 hours before, no water 1 hour before scan, strict PET diet 24 hours before scan (low carb, low sugar, high protein)
Colonoscopy Clear Liquid Diet the day prior
NPO except bowel prep from midnight day of to 2 hours before
See “Inpatient Colonoscopy Preparation” Order Panel in Epic

*In general, but subject to change depending on type of procedures 

**By convention, not necessarily data-driven. Multiple trials including CALORI, SCOFF, and TONIC demonstrate that normal diet is non-inferior (and in some cases superior) to NPO. 

Things that typically do NOT require a patient to be NPO: Medicine or CT-guided procedures such as paracentesis, thoracentesis, abscess/joint aspirations, lumbar punctures.


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